In the In the Know: STDs -The Invisible War video teen audiences will learn about the dangers of premarital and unprotected sex, and unsafe drug use.

The dangers, discussed by a teenage boy and girl hosts, include contracting chlamydia, genital herpes, HIV and AIDS, pubic lice (crabs), and syphilis.

The effects of each disease are explicitly discussed, including how they are treated.

In this version safe sex, such as condom use, is suggested. Also available in an Abstinence Only version.